The AAPS Journal - Themed Issue

2005 AAPS National Biotechnology Conference Open Forum - Aggregation of Protein Therapeutics
Guest Editor: Steve J. Shire

Table of Contents

Effects of Protein Aggregates: An Immunologic Perspective
Amy S. Rosenberg

Is Any Measurement Method Optimal for All Aggregate Sizes and Types?
John S. Philo

Protein Aggregation and Bioprocessing
Mary E.M. Cromwell, Eric Hilario, and Fred Jacobson

A Critical Review of Analytical Ultracentrifugation and Field Flow Fractionation Methods for Measuring Protein Aggregation
Jun Liu, James D. Andya, and Steven J. Shire

Role of Analytical Ultracentrifugation in Assessing the Aggregation of Protein Biopharmaceuticals
Steven A. Berkowitz

Concluding Summary: Proceedings of The AAPS Biotec Open Forum on "Aggregation of Protein Therapeutics."
Steven J. Shire, Mary Cromwell, Jun Liu