The AAPS Journal - Themed Issue

Role of Biomarkers in Drug Development
Guest Editors: Brian P. Booth and Jogarao V. Gobburu

Table of Contents

Commentary: Where and How Could Biomarkers Be Used in 2016
M. J. Finley Austin and Lee Babiss

Safety Biomarkers and the Clinical Development of Oncology Therapeutics: Considerations for Cardiovascular Safety and Risk Management
Howard Fingert and Mary Varterasian

Blood Pressure as an Example of a Biomarker That Functions as a Surrogate
Mehul Desai, Norman Stockbridge, and Robert Temple

Biomarker Qualification Pilot Process at the US Food and Drug Administration
Federico Goodsaid and Felix Frueh

Biomarkers, Metabonomics, and Drug Development: Can Inborn Errors of Metabolism Help in Understanding Drug Toxicity?
Subrahmanyam Vangala and Alfred Tonelli