The AAPS Journal - Themed Issue

Drug-Induced Hypersensitivity Reactions
Guest Editor: Craig Svensson

Table of Contents

Mechanisms of Drug-induced Delayed-type Hypersensitivity Reactions in the Skin
Sanjoy Roychowdhury and Craig K. Svensson

Role of Animal Models in the Study of Drug-induced Hypersensitivity Reactions
Jack Uetrecht

Genetic Factors in the Predisposition to Drug-induced Hypersensitivity Reactions
Munir Pirmohamed

Mechanisms of Drug-Induced Liver Injury
Michael P. Holt and Cynthia Ju

Role of Bioactivation in Drug-Induced Hypersensitivity Reactions
Joseph P. Sanderson, Dean J. Naisbitt, and B. Kevin Park

Noncovalent Interactions of Drugs With Immune Receptors May Mediate Drug-induced Hypersensitivity Reactions
Basil O. Gerber and Werner J. Pichler

Commentary: Drug Hypersensitivity — Where Do We Stand?
Craig K. Svensson