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Volume 08, Issue 03

Reviews
52 Multiple Molecular Targets in Cancer Chemoprevention by Curcumin
Rajesh L. Thangapazham, Anuj Sharma, Radha K. Maheshwari
[Abstract] [Full Text] [PDF]
53 New Paradigms and Tools in Drug Design for Pain and Addiction
Victor J. Hruby, Frank Porreca, Henry I. Yamamura, Gordon Tollin, Richard S. Agnes, Yeon Sun Lee, Minying Cai, Isabel Alves, Scott Cowell, Eva Varga, Peg Davis, Zdzislaw Salamon, William Roeske, Todd Vanderah, Josephine Lai
[Abstract] [Full Text] [PDF]
54 Targeted Lipidomics: Discovery of New Fatty Acyl Amides
Bo Tan, Heather B. Bradshaw, Neta Rimmerman, Harini Srinivasan, Y. William Yu, Jocelyn F. Krey, M. Francesca Monn, Jay Shih-Chieh Chen, Sherry Shu-Jung Hu, Sarah R. Pickens, J. Michael Walker
[Abstract] [Full Text] [PDF]
55 Issues Related to Targeted Delivery of Proteins and Peptides
Yingjuan Lu, Jun Yang, Emanuela Sega
[Abstract] [Full Text] [PDF]
56 Agmatine: Biological Role and Therapeutic Potentials in Morphine Analgesia and Dependence
Soundar Regunathan
[Abstract] [Full Text] [PDF]
59 Effects of Protein Aggregates: An Immunologic Perspective
Amy S. Rosenberg
[Abstract] [Full Text] [PDF]
60 MicroPET Investigation of Chronic Long-Term Neurotoxicity from Heavy Ion Irradiation
Onarae Rice, Sandra Saintvictor, Michael Michaelides, Panayotis Thanos, Samuel John Gatley
[Abstract] [Full Text] [PDF]
61 Searching for Polymorphisms That Affect Gene Expression and mRNA Processing: Example ABCB1 (MDR1)
Danxin Wang, Wolfgang Sadée
[Abstract] [Full Text] [PDF]
62 Mitochondria-Targeted Peptide Antioxidants: Novel Neuroprotective Agents
Hazel H. Szeto
[Abstract] [Full Text] [PDF]
63 Immunotoxins for Targeted Cancer Therapy
Robert J. Kreitman
[Abstract] [Full Text] [PDF]
65 Is Any Measurement Method Optimal for All Aggregate Sizes and Types?
John S. Philo
[Abstract] [Full Text] [PDF]
66 Protein Aggregation and Bioprocessing
Mary E.M. Cromwell, Eric Hilario, Fred Jacobson
[Abstract] [Full Text] [PDF]
67 A Critical Review of Analytical Ultracentrifugation and Field Flow Fractionation Methods for Measuring Protein Aggregation
Jun Liu, James D. Andya, Steven J. Shire
[Abstract] [Full Text] [PDF]
68 Role of Analytical Ultracentrifugation in Assessing the Aggregation of Protein Biopharmaceuticals
Steven A. Berkowitz
[Abstract] [Full Text] [PDF]
69 Modulation of Microglial Pro-inflammatory and Neurotoxic Activity for the Treatment of Parkinson’s Disease
Bin Liu
[Abstract] [Full Text] [PDF]
Original Research Articles
51 Pharmacokinetics and Bioavailability of the Isoflavone Biochanin A in Rats
Young Jin Moon, Kazuko Sagawa, Kosea Frederick, Shuzhong Zhang, Marilyn E. Morris
[Abstract] [Full Text] [PDF]
57 The Kinetics of Thiol-mediated Decomposition of S-Nitrosothiols
Teh-Min Hu, Ta-Chuan Chou
[Abstract] [Full Text] [PDF]
58 Rapid In Vivo Oral Screening in Rats: Reliability, Acceptance Criteria, and Filtering Efficiency
Hong Mei, Walter Korfmacher, Richard Morrison
[Abstract] [Full Text] [PDF]
64 Development and Evaluation of a Population Pharmacokinetic-Pharmacodynamic Model of Darbepoetin Alfa in Patients with Nonmyeloid Malignancies Undergoing Multicycle Chemotherapy
Balaji Agoram, Anne C. Heatherington, Marc R. Gastonguay
[Abstract] [Full Text] [PDF]
Corrigenda
70 Corrigendum: Current Status of Immunologic Approaches to Treating Tobacco Dependence: Vaccines and Nicotine-specific Antibodies
Mark G. LeSage, Daniel E. Keyler, Paul R. Pentel
[Full Text] [PDF]

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