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Volume 07, Issue 04

Reviews
78 The Role of Crystallography in Drug Design
Jeffrey R. Deschamps
[Abstract] [Full Text] [PDF]
79 Ophthalmic Drug Design Based on the Metabolic Activity of the Eye: Soft Drugs and Chemical Delivery Systems
Nicholas Bodor, Peter Buchwald
[Abstract] [Full Text] [PDF]
80 Mechanisms of Drug-induced Delayed-type Hypersensitivity Reactions in the Skin
Sanjoy Roychowdhury, Craig K. Svensson
[Abstract] [Full Text] [PDF]
81 Role of Monoamine Transporters in Mediating Psychostimulant Effects
Evan L. Riddle, Annette E. Fleckenstein, Glen R. Hanson
[Abstract] [Full Text] [PDF]
82 Transport Systems for Opioid Peptides in Mammalian Tissues
Vadivel Ganapathy, Seiji Miyauchi
[Abstract] [Full Text] [PDF]
84 Viewing Chemokines as a Third Major System of Communication in the Brain
Martin W. Adler, Ellen B. Geller, Xiaohong Chen, Thomas J. Rogers
[Abstract] [Full Text] [PDF]
85 Hallucinogen Actions on 5-HT Receptors Reveal Distinct Mechanisms of Activation and Signaling by G Protein-coupled Receptors
Harel Weinstein
[Abstract] [Full Text] [PDF]
86 Neuronal Nicotinic Acetylcholine Receptor Expression and Function on Nonneuronal Cells
Lorise C. Gahring, Scott W. Rogers
[Abstract] [Full Text] [PDF]
89 Role of Animal Models in the Study of Drug-induced Hypersensitivity Reactions
Jack Uetrecht
[Abstract] [Full Text] [PDF]
Original Research Articles
76 Simultaneous Population Optimal Design for Pharmacokinetic-Pharmacodynamic Experiments
Andrew Hooker, Paolo Vicini
[Abstract] [Full Text] [PDF]
77 Equivalence Studies for Complex Active Ingredients and Dosage Forms
Lokesh Bhattycharyya, Roger Dabbah, Walter Hauck, Eric Sheinin, Lynn Yeoman, Roger Williams
[Abstract] [Full Text] [PDF]
83 Shear-induced Variability in the United States Pharmacopeia Apparatus 2: Modifications to the Existing System
Jennifer L. Baxter, Joseph Kukura, Fernando J. Muzzio
[Abstract] [Full Text] [PDF]
87 Pharmacokinetic and Pharmacodynamic Effects of High-Dose Monoclonal Antibody Therapy in a Rat Model of Immune Thrombocytopenia
Feng Jin, Zia R. Tayab, Joseph P. Balthasar
[Abstract] [Full Text] [PDF]
88 Microencapsulation of Hemoglobin in Chitosan-coated Alginate Microspheres Prepared by Emulsification/Internal Gelation
Catarina M. Silva, António J. Ribeiro, Margarida Figueiredo, Domingos Ferreira, Francisco Veiga
[Abstract] [Full Text] [PDF]
90 N-n-Alkylnicotinium Analogs, a Novel Class of Antagonists at a4ß2* Nicotinic Acetylcholine Receptors: Inhibition of S(-)-Nicotine-Evoked 86Rb+ Efflux from Rat Thalamic Synaptosomes
Lincoln H. Wilkins, Dennis K. Miller, Joshua T. Ayers, Peter A. Crooks, Linda P. Dwoskin
[Abstract] [Full Text] [PDF]

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