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Volume 02, Issue 01

Articles
1 Pharmacokinetics of Nevirapine and Lamivudine in Patients with HIV-1 Infection
John P. Sabo, Michael J. Lamson, Gerhard Leitz, Chan-Loi Yong, Thomas R. MacGregor
2 Molecular Modeling of G-protein Coupled Receptor Kinase 2: Docking and Biochemical Evaluation of Inhibitors
Matthias U. Kassack, Petra Högger, Daniel A. Gschwend, Kimihiko Kameyama, Tatsuya Haga, Richard C. Graul, Wolfgang Sadée
3 Maturation and Growth of Renal Function: Dosing Renally Cleared Drugs in Children
William L. Hayton
4 Pharmacogenomics: The Promise of Personalized Medicine
Laviero Mancinelli, Maureen Cronin, Wolfgang Sadée
5 Comparison of the Rates of Deamidation, Diketopiperazine Formation and Oxidation in Recombinant Human Vascular Endothelial Growth Factor and Model Peptides
Chimanlall Goolcharran, Jeffrey L. Cleland, Rodney Keck, Andrew J.S. Jones, Ronald T. Borchardt
6 Targeted Prodrug Design to Optimize Drug Delivery
Hyo-Kyung Han, Gordon L. Amidon
7 Synthesis and Characterization of Positively Charged tPA as a Prodrug Using Heparin/Protamine-Based Drug Delivery System
Jun F. Liang, Yong T. Li, Maureen E. Connell, Victor C. Yang
8 Comparison of Methods for Analyzing Kinetic Data From Mechanism-Based Enzyme Inactivation: Application to Nitric Oxide Synthase
Tristan Maurer, Ho-Leung Fung
9 Comparative Evaluation of the Degree of Indomethacin Crystallinity by Chemoinfometrical Fourie-Transformed Near-Infrared Spectroscopy and Conventional Powder X-ray Diffractiometry
Makoto Otsuka, Fumie Kato, Yoshihisa Matsuda
Editorial - E-Publishing in 2000
Wolfgang Sadée

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