Figure 1. Macromedia Flash animations of the following processes: (A) Activity of an antigene oligonucleotide; (B) Activity of an antisense oligonucleotide; (C) Activity of an aptamer; (D) Activity of DNAzyme; (E) Activity of RNAzyme; (F) Activity of a siRNA; and (G) Activity of a plasmid therapeutic. The reader may access the interactive and animated user-controlled interface online, select the type of DNA-based therapeutic, and observe a detailed graphic animation of the specific processes involved in its uptake, subsequent intracellular fate, and mechanism of action.

To view the Flash animations, you must install Macromedia's Flash Player, available at http://www.macromedia.com.